Major depression D/D

Major depression with psychosis:
Major depression has the psychomotor retardation. Typical vegetative symptoms include anorexia, weight loss and insomnia, particularly early morning awakening. Psychotic symptoms such as delusions and hallucinations may occur in depression, and when they do, treatment with both an antidepressant and an antipsychotic is indicated.

In alcohol-induced psychotic disorder with hallucinations, the patient may have auditory hallucinations, usually voices. The voices are characteristically maligning, reproachful or threatening. The hallucinations usually last less than a week. After the episode, most patients realise the hallucinatory nature of the symptoms.

Korsakoff's psychosis is characterised by both anterograde and retrograde amnesia, with confabulation early in the course. In psychotic depression, the depression is of psychotic intensity with delusional convictions of disease, putrefaction and poverty, contaminating others or causing evil. There may also be hallucinations, typically accusing or derogatory voices.

Core symptoms of schizophrenia are delusions, hallucinations, disorganised speech, negative symptoms (e.g. blunted affect and poverty of speech) and disorganised behaviour.