Tolvaptan, a Selective Oral Vasopressin V2-Receptor Antagonist, for Hyponatremia

In patients with euvolemic or hypervolemic hyponatremia, tolvaptan, an oral vasopressin V2-receptor antagonist, was effective in increasing serum sodium concentrations at day 4 and day 30.

http://content.nejm.org/cgi/content/abstract/355/20/2099