My consultant neurologist normally prescribes the patients with stroke: Aspirin, Ramipril,Statin.This ESPS-2 shows there is a benefit of adding dipyridamole. It was done in 1988. so there should be more research data somewhere. [b]European Stroke Prevention Study 2 (ESPS-2):[/b] After doing randomised, double-blind, placebo-controlled trial of 6602 patients, it was discovered that the 24-month stroke rate was 12.9% in the aspirin-alone group, 13.2% in the dipyridamole-alone group, 9.9% in the combination group and 15.8% in the placebo group. Stroke risk was significantly reduced by 18.1% in the aspirin-alone group, by 16.3% in the dipyridamole-alone group, and by 37.0% in the combination group compared to the placebo group. The results regarding the endpoint of stroke or death were similar but there was no significant difference among the groups for the endpoint of death . [url=http://www.ncbi.nlm.nih.gov]source[/url]